Santana, Angels beat Indians 8-4

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ANAHEIM, Calif. (AP) -- Mike Trout and Chris Iannetta homered to help the Los Angeles Angels build a big lead against Roberto Hernandez in his season debut with Cleveland, and Ervin Santana breezed to an 8-4 victory over the Indians on Wednesday night.

Santana (6-10) allowed a run and four hits in seven innings, struck out four and walked one. The only run came on a sixth-inning double by Asdrubal Cabrera. Santana, whose only other victory against the Indians was a no-hitter at Cleveland on July 27, 2001, is 2-8 in 14 career starts against the Tribe.

Jason Isringhausen gave up a three-run homer in the eighth to Shin-Soo Choo, his 14th this season, but Kevin Jepsen closed it out with a perfect ninth.

Hernandez, formally known as Fausto Carmona, was added to the Indians' 25-man roster on Tuesday after fellow right-hander Josh Tomlin was placed on the 15-day disabled list because of inflammation in his elbow.