The host Wildcats jumped out to a 19-point lead through three quarters, then cruised to the victory.
Matt Braaten scored 14 points to lead La Center (6-4). Dylan King added nine points with six rebounds and three assists.
Jeremiah Arn had six points and also showcased his defensive skills with seven steals.
Austin Myers led La Center with eight rebounds. He also had two blocked shots.
LA CENTER 49, ROCHESTER 41
ROCHESTER — Ayala 9, Gedney 9, Vanderwoof 2, Carey 2, Grimmett 14, Smith 5, Bigsbe 0, Gutierrez 0. Totals 15-48(3) 8-20 41.
LA CENTER (6-4) — Connor Wonderly 8, Scott Barger 0, Jeremiah Arn 6, Dylan King 9, Matt Braaten 14, Jon Griffee 0, Zach Brown 2, Austin Myers 5, Levi Van Tol 4, Josh Soske 0, Daniel Evans 1. Totals 16-52 (3) 14-22 49.
Rochester 7 2 7 25—41
La Center 12 9 14 14—49
JV — La Center won