Jordan Ryan scored 19 points to lead the Chieftains to a win in their season opener.
Erin Baker added 15 points, Sydney Flores Tucker scored 11 and Ellie Christian had 10.
The Chieftains jumped to a 20-6 lead after one quarter and led 39-13 at halftime.
Jasmine Morgan scored 10 points to lead Seton Catholic (0-2).
COLUMBIA RIVER 65, SETON CATHOLIC 29
COLUMBIA RIVER — Sami Myers 3, Liz Canton 4, Halle Jordan 3, Lily Jonas 0, Sydney Flores-Tucker 11, Erin Baker 15, Gatten 0, Ari Kuschner 0, Jordan Ryan 19, Ellie Christian 10. Totals 24 (12) 5-7 65.
SETON CATHOLIC — Haley Vick 2, Michaela Ephraim 0, Emma Watkins 2, Katie Willis 6, Jasmine Morgan 10, Madi Manary 0, Claire Kirn 0, Jerrica Pachl 6, Aislynn Hogan 0, Maddie Willis 3, Cailean McGovern 0, Katherine Zdunich 0. Totals 10 (3) 6-10 29.
