By the time sailing ship Capt. Robert Gray named and claimed the Columbia River for the United States in 1792, European diseases already had decimated the Pacific Northwest Native American population. Later outbreaks — influenza (1836), malaria (1830s), measles (1830s and 1840s), smallpox (1781 to 1863) and shigellosis (1844) — killed more.
It’s estimated that diseases wiped out 90 percent of America’s Indigenous population. Diseases progressed along river trade routes. When Lewis and Clark traveled to the Pacific Ocean, they often used the phrase “destroyed by the Small Pox” when seeing empty villages. Native Americans were particularly susceptible to dying from European diseases, as they had developed no immunity to them.
During the summers of the mid-1970s, archaeologists uncovered the remains of several Hudson’s Bay Company buildings located southwest of Fort Vancouver on a slender land strip between the railroad tracks and state Highway 14. One was a hospital, likely to have been placed outside the fort and away from the Kanaka Village to protect company employees from contagious and epidemic diseases.
A Fort Vancouver physician, Dr. Forbes Barclay, noted around 1840 that a measles epidemic had infected Native Americans during the first quarter of the 19th century. In 1847-1849, another measles epidemic hit the Oregon Territory. The outbreak among the Cayuse people led to their attack on the Whitman Mission at Walla Walla, killing Dr. Marcus Whitman and others after the doctor failed to cure them of the plague.