You wouldn’t think that dissolving part of the brain, particularly one that helps hold the organ together, would help a gerbil rethink a problem.
But that’s exactly what a team of German scientists has done.
Their results, published online this week in the journal Proceedings of the National Academy of Sciences, suggest that a lot more is going on in the spaces between neurons, and an area of the brain once thought of as a simple processor may be more like a calculator.
Researchers from the Leibniz Institute for Neurobiology in Magdeburg were focusing on a microscopic scaffold that stabilizes the synapses, the tiny gaps where electrochemical signals are relayed between neurons.
There already were clues that this so-called extracellular matrix, which comes into place as the brain matures, did much more than just hold things together. Injecting enzymes to digest this matrix seemed to put animal brains in a more youthful state where neuron pathways could be altered, previous research had shown.