A team of Pittsburgh researchers has discovered a genetic mutation that aided the spread of breast cancer in a patient, an exciting discovery that may provide guidance for how to treat women with the disease in the future, according to a study announced recently at a breast cancer symposium in San Antonio.
The team of researchers from the University of Pittsburgh Cancer Institute and the Magee-Womens Research Institute used tumor tissue samples collected over the last two decades that allowed researchers to track the spread of the disease in six patients.
All six patients had surgery to remove the initial tumor, and were determined to be disease free, only to have the cancer recur and ultimately kill them. Recurrence of breast cancer after surgery occurs in about 30 percent of patients.
While the main finding revealed Wednesday revolved around the one genetic mutation, research continues with the results of the tissue studies from the other five patients, which are also expected to provide insights into how breast cancer operates.