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News / Health / Health Wire

Outlook shifting on pancreatic cancer

By Mayo Clinic News Network
Published: November 24, 2020, 6:20am

ROCHESTER, Minn. — Pancreatic cancer often is hidden and doesn’t cause symptoms until it has spread. It is a leading cause of cancer deaths.

Nov. 19 is World Pancreatic Cancer Day, but the entire month of November is meant to bring awareness to this disease.

Advances in screening and early detection for high-risk people, minimally invasive surgical innovations and new genetic classifications are changing the outlook for pancreatic cancer, says Dr. Michael Wallace, a Mayo Clinic gastroenterologist.

Some of the benefits include:

Thanks to advances in MRI technology, doctors today can identify pancreatic cysts, small saclike pockets of fluid that may increase the risk for cancer.

Patients with large tumors now can take advantage of improved chemotherapy to shrink the tumors prior to surgery.

Today, thanks to fine needle biopsies, physicians can get enough of the cancerous material and look at genetic sequences to see if there is a better medication available when current options are exhausted.

In addition, for a small number of pancreatic cancer cases, one clue can help doctors find the tumor early. That clue is an unexpected diagnosis of diabetes. In these cases, the pancreatic cancer is actually causing the diabetes, Wallace says.

And the key feature is that the diabetes appears where you wouldn’t expect it — such as in someone who is maintaining or losing weight, or someone who gets diabetes at an older age.

Wallace and colleagues are focused on early detection.

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